Experimental in vitro infection of rat osteoblasts with measles virus stimulates osteogenic differentiation

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In this work we characterized the infection of a primary culture of rat osteoblastic lineage cells (OBCs) with measles virus (MeV) and the effect of infection on cell differentiation and maturation. Infection of OBCs with MeV led to high titers of infectivity released early after infection. Also, an...

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Detalles Bibliográficos
Autores principales: Ayala-Peña, V., Santillán, G., Scolaro, L.
Formato: JOUR
Materias:
Bone morphogenetic proteins
Differentiation
Measles virus
Osteoblasts
Otosclerosis
2 morpholino 8 phenylchromone
adenosine triphosphate
alkaline phosphatase
bone morphogenetic protein 4
bone morphogenetic protein 5
bone sialo protein
messenger RNA
osteogenic protein 1
phosphatidylinositol 3 kinase
procollagen C proteinase
protein
protein kinase B
unclassified drug
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one
adenosine 5' o (3 thiotriphosphate)
adenosine 5'-O-(3-thiotriphosphate)
bone morphogenetic protein
chromone derivative
drug derivative
morpholine derivative
animal cell
animal experiment
animal model
Article
bone development
cell differentiation
controlled study
experimental infection
in vitro study
measles
nonhuman
osteoblast
protein expression
rat
stimulation
virus load
animal
article
biosynthesis
bone
cell culture
differentiation
drug antagonism
drug effect
metabolism
otosclerosis
physiology
virology
virus replication
Adenosine Triphosphate
Alkaline Phosphatase
Animals
Bone and Bones
Bone Morphogenetic Protein 4
Cell Differentiation
Cells, Cultured
Chromones
Morpholines
Osteogenesis
Phosphatidylinositol 3-Kinases
Rats
Virus Replication
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_0006291X_v451_n4_p609_AyalaPena
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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