Bradykinin stimulates phospholipase C in rat renal medullary slices

Rat renal medullary slices prelabeled with [14C]arachidonic acid generate [14C]diacylglycerol within 1 min of exposure to bradykinin action. Production of [14C]diacylglycerol is transient. 2 min after the addition of bradykinin, the levels of metabolite reach the maximun, but decrease thereafter. Si...

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Detalles Bibliográficos
Autores principales: Speziale, N., Speziale, E.H., Pasquini, J.M.
Formato: JOUR
Materias:
(Rat kidney medulla)
Bradykinin
Diacylglycerol
Phosphatidylinositol
Phospholipase C
bradykinin
bucladesine
enzyme
indometacin
mepacrine
phosphatidylinositol
phospholipase c
radioisotope
animal cell
arachidonic acid c 14
diacylglycerol c 14
dose response
drug comparison
drug elimination
drug inhibition
drug mechanism
drug metabolism
drug monitoring
drug response
kidney
kidney medulla
nonhuman
phosphatidylinositol c 14
priority journal
rat
thin layer chromatography
Animal
Bucladesine
Diglycerides
Enzyme Activation
Indomethacin
Kidney Medulla
Male
Phosphatidylinositols
Phospholipases
Phospholipids
Quinacrine
Rats
Rats, Inbred Strains
Support, Non-U.S. Gov't
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00052760_v836_n1_p14_Speziale
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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