In Silico Structural and Functional Characterization of the RSUME Splice Variants

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RSUME (RWD-containing SUMO Enhancer) is a small protein that increases SUMO conjugation to proteins. To date, four splice variants that codify three RSUME isoforms have been described, which differ in their C-terminal end. Comparing the structure of the RSUME isoforms we found that, in addition to t...

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Autores principales: Gerez, J., Fuertes, M., Tedesco, L., Silberstein, S., Sevlever, G., Paez-Pereda, M., Holsboer, F., Turjanski, A.G., Arzt, E.
Formato: Artículo publishedVersion
Lenguaje:Inglés
Publicado: 2013
Materias:
hypoxia inducible factor 1
immunoglobulin enhancer binding protein
messenger RNA
protein variant
regulator protein
RWD containing SUMO enhancer protein
SUMO protein
unclassified drug
isoprotein
RSUME protein, human
SUMO 1 protein
transcription factor
article
brain cancer
carboxy terminal sequence
computer model
controlled study
gene expression
human
human tissue
molecular pathology
molecular weight
nucleotide sequence
protein domain
protein expression
protein function
protein processing
protein protein interaction
regulator gene
RWD containing SUMO enhancer gene
signal transduction
structure activity relation
structure analysis
amino acid sequence
animal
biology
cell line
chemical structure
chemistry
gene expression regulation
genetics
metabolism
molecular genetics
protein secondary structure
Amino Acid Sequence
Animals
Cell Line
Computational Biology
Gene Expression Regulation
Humans
Hypoxia-Inducible Factor 1
Models, Molecular
Molecular Sequence Data
NF-kappa B
Protein Isoforms
Protein Structure, Secondary
Signal Transduction
SUMO-1 Protein
Transcription Factors
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_19326203_v8_n2_p_Gerez
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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