Bayesian Approach to Model CD137 Signaling in Human M. tuberculosis In Vitro Responses

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Immune responses are qualitatively and quantitatively influenced by a complex network of receptor-ligand interactions. Among them, the CD137:CD137L pathway is known to modulate innate and adaptive human responses against Mycobacterium tuberculosis. However, the underlying mechanisms of this regulati...

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Detalles Bibliográficos
Autores principales: Fernández Do Porto, D.A., Auzmendi, J., Peña, D., García, V.E., Moffatt, L.
Formato: Artículo publishedVersion
Lenguaje:Inglés
Publicado: 2013
Materias:
CD137 antigen
cytokine
gamma interferon
tuberculostatic agent
tumor necrosis factor alpha
antigen presenting cell
article
Bayes theorem
cell survival
clinical article
culture medium
cytokine production
human
immune response
in vitro study
lung tuberculosis
Monte Carlo method
Mycobacterium tuberculosis
natural killer cell
nonhuman
nonlinear system
probability
qualitative analysis
quantitative analysis
T lymphocyte
thermodynamics
4-1BB Ligand
Adaptive Immunity
Adult
Antigen-Presenting Cells
Antigens, CD137
Antigens, CD56
Bayes Theorem
Cellular Microenvironment
Cytokines
Humans
Immunity, Innate
Intracellular Space
Killer Cells, Natural
Models, Biological
Signal Transduction
T-Lymphocytes
Thermodynamics
Tuberculosis
Uncertainty
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_19326203_v8_n2_p_FernandezDoPorto
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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