Continuous nonradioactive method for screening trypanosomal transsialidase activity and its inhibitors

Trypanosoma cruzi, the agent of American trypanosomiasis is unable to synthesize sialic acid (SA). Instead of using the corresponding nucleotide sugar as donor of the monosaccharide, the transfer occurs from α-2,3-linked SA in the host sialoglycoconjugates to terminal β-galactopyranosyl units of the...

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Autores principales: Sartor, P.A., Agusti, R., Leguizamón, M.S., Campetella, O., de Lederkremer, R.M.
Formato: Artículo publishedVersion
Lenguaje:Inglés
Publicado: 2010
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Acceso en línea:http://hdl.handle.net/20.500.12110/paper_09596658_v20_n8_p982_Sartor
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