Impairment of mineralocorticoid receptor (MR)-dependent biological response by oxidative stress and aging: Correlation with post-translational modification of MR and decreased ADP-ribosylatable level of elongation factor 2 in kidney cells
Acute and chronic treatments of mice with the glutathione-depleting agent, L-buthionine-(SR)-sulfoximine (BSO), impaired the mineralocorticoid receptor (MR)-dependent biological response by inhibiting aldosterone binding. This steroid-binding inhibition was fully reversed when reducing agents were a...
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Autores principales: | , , , |
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Formato: | Artículo publishedVersion |
Lenguaje: | Inglés |
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2002
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Materias: | |
Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_00219258_v277_n14_p11896_PiwienPilipuk |
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