A mucin-like peptide from Fasciola hepatica instructs dendritic cells with parasite specific Th1-polarizing activity

Fasciolosis is a trematode zoonosis of interest in public health and cattle production. We report here the immunostimulatory effect of a 66 mer mucin-like peptide from Fasciola hepatica (Fhmuc), which synergizes with lipopolysaccharide (LPS) to promote dendritic cell (DC) maturation, endowing these...

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Detalles Bibliográficos
Publicado:	2017
Materias:	antibody autacoid cytokine gamma interferon glycoprotein p 15095 helminth antibody immunoglobulin enhancer binding protein immunoglobulin G lipopolysaccharide mucin 1 peptide toll like receptor 4 animal biological model C57BL mouse cell polarity cytology dendritic cell drug effect Fasciola hepatica female immunology lymphocyte activation metabolism parasite pathology peritoneal cavity signal transduction species difference spleen Th1 cell vaccination Animals Antibodies Antibodies, Helminth CD11c Antigen Cell Polarity Cytokines Dendritic Cells Female Immunoglobulin G Inflammation Mediators Interferon-gamma Lipopolysaccharides Lymphocyte Activation Mice, Inbred C57BL Models, Biological Mucin-1 NF-kappa B Parasites Peptides Peritoneal Cavity Signal Transduction Species Specificity Spleen Th1 Cells Toll-Like Receptor 4 Vaccination
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_20452322_v7_n_p_Noya http://hdl.handle.net/20.500.12110/paper_20452322_v7_n_p_Noya
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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