Broad MICA/B Expression in the Small Bowel Mucosa: A Link between Cellular Stress and Celiac Disease

The MICA/B genes (MHC class I chain related genes A and B) encode for non conventional class I HLA molecules which have no role in antigen presentation. MICA/B are up-regulated by different stress conditions such as heat-shock, oxidative stress, neoplasic transformation and viral infection. Particul...

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Detalles Bibliográficos
Publicado:	2013
Materias:	CD20 antigen CD3 antigen CD68 antigen CD7 antigen glycoprotein p 15095 major histocompatibility antigen class 1 major histocompatibility antigen class 2 syndecan 1 article B lymphocyte celiac disease cell stress cellular distribution child clinical article confocal microscopy controlled study disease severity endoplasmic reticulum stress flow cytometry gene gene expression regulation human human cell human tissue immune dysregulation immunofluorescence test immunopathogenesis intestine biopsy lamina propria macrophage MICA gene MICAB gene oxidative stress preschool child protein localization small intestine mucosa B-Lymphocytes Celiac Disease Child, Preschool Duodenum Enterocytes Female Gene Expression Histocompatibility Antigens Class I Humans Intestinal Mucosa Macrophages Male Plasma Cells Severity of Illness Index Stress, Physiological T-Lymphocytes
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_19326203_v8_n9_p_Allegretti http://hdl.handle.net/20.500.12110/paper_19326203_v8_n9_p_Allegretti
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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