Chromatin Relaxation-Mediated Induction of p19INK4d Increases the Ability of Cells to Repair Damaged DNA

The maintenance of genomic integrity is of main importance to the survival and health of organisms which are continuously exposed to genotoxic stress. Cells respond to DNA damage by activating survival pathways consisting of cell cycle checkpoints and repair mechanisms. However, the signal that trig...

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Detalles Bibliográficos
Autores principales:	Ogara, Maria Florencia, Carcagno, Abel Luis, Marazita, Mariela C., Sonzogni, Silvina Verónica, Ceruti, Julieta María, Cánepa, Eduardo Tomás
Publicado:	2013
Materias:	ATM protein ATR protein checkpoint kinase 1 checkpoint kinase 2 cyclin dependent kinase inhibitor 2D transcription factor E2F article cell cycle regulation cell function chromatin chromatin relaxation chromatin structure controlled study DNA repair enzyme activity genotoxicity human human cell protein induction signal transduction Cell Cycle Proteins Cell Line Chloroquine Chromatin Cyclin-Dependent Kinase Inhibitor p19 DNA Damage DNA Repair DNA-Binding Proteins E2F1 Transcription Factor Humans Models, Biological Mutagens Protein Kinases Protein-Serine-Threonine Kinases Signal Transduction Tumor Suppressor Proteins Ultraviolet Rays
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_19326203_v8_n4_p_Ogara http://hdl.handle.net/20.500.12110/paper_19326203_v8_n4_p_Ogara
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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