Structural analysis of the N-glycans of the major cysteine proteinase of Trypanosoma cruzi: Identification of sulfated high-mannose type oligosaccharides

Trypanosoma cruzi, the parasitic protozoan that causes Chagas disease, contains a major cysteine proteinase, cruzipain. This lysosomal enzyme bears an unusual C-terminal extension that contains a number of post-translational modifications, and most antibodies in natural and experimental infections a...

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Detalles Bibliográficos
Publicado:	2005
Materias:	Cruzipain Nor-harmane Sulfated oligosaccharides Trypanosoma cruzi UV-MALDI-TOF MS cruzipain cysteine proteinase deoxysugar glycan glycosidase mannose oligosaccharide anion exchange chromatography article carboxy terminal sequence deglycosylation fucosylation matrix assisted laser desorption ionization time of flight mass spectrometry nonhuman priority journal protein analysis sialylation structure analysis sulfation Animals Cysteine Endopeptidases Electrophoresis, Polyacrylamide Gel Fucose Mannose Oligosaccharides, Branched-Chain Silver Staining Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Time Factors Protozoa Trypanosomatidae
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_1742464X_v272_n15_p3803_Barboza http://hdl.handle.net/20.500.12110/paper_1742464X_v272_n15_p3803_Barboza
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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