PEST Control of Molecular Stripping of NFκB from DNA Transcription Sites

We recently proposed a model for IκBα-mediated molecular stripping of NFκB from transcription sites. IκBα was shown experimentally to form a transient ternary complex with DNA-bound NFκB, but the mechanism by which the IκBα accelerates dissociation of the NFκB from the DNA was unknown. In this paper...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autor principal: Ferreiro, Diego U.
Publicado: 2016
Materias:
Bins
Free energy
Transcription
Binary complexes
DNA transcriptions
N-terminal domains
Negative charge
Negatively charged
Positively charged
Specific interaction
Ternary complex
DNA
I kappa B kinase alpha
immunoglobulin enhancer binding protein
chemistry
computer simulation
genetic transcription
metabolism
molecular model
protein domain
Computer Simulation
Models, Molecular
NF-kappa B
NF-KappaB Inhibitor alpha
Protein Domains
Transcription, Genetic
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_15206106_v120_n33_p8532_Potoyan
http://hdl.handle.net/20.500.12110/paper_15206106_v120_n33_p8532_Potoyan
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

Ejemplares similares

Ejemplares similares