An efficient chemoenzymatic synthesis of the bactericide lapyrium chloride

An efficient route for large-scale preparation of lapyrium chloride, a broad-spectrum antimicrobial surfactant, was developed from chloroacetic acid in four steps, three of them enzymatic. Due to the chemoselective behavior of the biocatalysts, lapyrium chloride was obtained in a high degree of puri...

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Autores principales: Rustoy, Eduardo Miguel, Baldessari, Alicia
Publicado: 2005
Materias:
Aminolysis
Bactericide
Enzyme-catalyzed acylation
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_1434193X_v_n21_p4628_Rustoy
http://hdl.handle.net/20.500.12110/paper_1434193X_v_n21_p4628_Rustoy
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id paper:paper_1434193X_v_n21_p4628_Rustoy
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spelling paper:paper_1434193X_v_n21_p4628_Rustoy2023-06-08T16:14:25Z An efficient chemoenzymatic synthesis of the bactericide lapyrium chloride Rustoy, Eduardo Miguel Baldessari, Alicia Aminolysis Bactericide Enzyme-catalyzed acylation An efficient route for large-scale preparation of lapyrium chloride, a broad-spectrum antimicrobial surfactant, was developed from chloroacetic acid in four steps, three of them enzymatic. Due to the chemoselective behavior of the biocatalysts, lapyrium chloride was obtained in a high degree of purity and yield, from mild reaction conditions and following a low environmental impact methodology. © Wiley-VCH Verlag GmbH & Co. KGaA, 2005. Fil:Rustoy, E.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Baldessari, A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 2005 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_1434193X_v_n21_p4628_Rustoy http://hdl.handle.net/20.500.12110/paper_1434193X_v_n21_p4628_Rustoy
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Aminolysis
Bactericide
Enzyme-catalyzed acylation
spellingShingle Aminolysis
Bactericide
Enzyme-catalyzed acylation
Rustoy, Eduardo Miguel
Baldessari, Alicia
An efficient chemoenzymatic synthesis of the bactericide lapyrium chloride
topic_facet Aminolysis
Bactericide
Enzyme-catalyzed acylation
description An efficient route for large-scale preparation of lapyrium chloride, a broad-spectrum antimicrobial surfactant, was developed from chloroacetic acid in four steps, three of them enzymatic. Due to the chemoselective behavior of the biocatalysts, lapyrium chloride was obtained in a high degree of purity and yield, from mild reaction conditions and following a low environmental impact methodology. © Wiley-VCH Verlag GmbH & Co. KGaA, 2005.
author Rustoy, Eduardo Miguel
Baldessari, Alicia
author_facet Rustoy, Eduardo Miguel
Baldessari, Alicia
author_sort Rustoy, Eduardo Miguel
title An efficient chemoenzymatic synthesis of the bactericide lapyrium chloride
title_short An efficient chemoenzymatic synthesis of the bactericide lapyrium chloride
title_full An efficient chemoenzymatic synthesis of the bactericide lapyrium chloride
title_fullStr An efficient chemoenzymatic synthesis of the bactericide lapyrium chloride
title_full_unstemmed An efficient chemoenzymatic synthesis of the bactericide lapyrium chloride
title_sort efficient chemoenzymatic synthesis of the bactericide lapyrium chloride
publishDate 2005
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_1434193X_v_n21_p4628_Rustoy
http://hdl.handle.net/20.500.12110/paper_1434193X_v_n21_p4628_Rustoy
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AT baldessarialicia anefficientchemoenzymaticsynthesisofthebactericidelapyriumchloride
AT rustoyeduardomiguel efficientchemoenzymaticsynthesisofthebactericidelapyriumchloride
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