Galectin-1 as an Emerging Mediator of Cardiovascular Inflammation: Mechanisms and Therapeutic Opportunities

Galectin-1 (Gal-1), an evolutionarily conserved β-galactoside-binding lectin, controls immune cell homeostasis and tempers acute and chronic inflammation by blunting proinflammatory cytokine synthesis, engaging T-cell apoptotic programs, promoting expansion of T regulatory (Treg) cells, and deactiva...

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Detalles Bibliográficos
Publicado:	2018
Materias:	ecalectin galectin galectin 1 galectin 12 glycan unclassified drug vasculotropin receptor vasculotropin A acute heart infarction antiinflammatory activity atherosclerosis brain ischemia cell differentiation cell expansion cell survival Chagas cardiomyopathy cytokine production heart failure immunocompetent cell mediator pulmonary hypertension regulatory T lymphocyte Review animal homeostasis human inflammation metabolism physiology Animals Galectin 1 Homeostasis Humans Inflammation T-Lymphocytes, Regulatory Vascular Endothelial Growth Factor A
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09629351_v2018_n_p_Seropian http://hdl.handle.net/20.500.12110/paper_09629351_v2018_n_p_Seropian
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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