Early effects of insulin-like growth factor-1 in activated human T lymphocytes

This study evaluates the effects of insulin-like growth factor (IGF)-1 receptor (IGF-1R) down-regulation in stimulated T lymphocytes by investigating the expression of early activation proteins CD69, CD25, and interleukin (IL)-2. We found that IGF-1 does not modify CD69 expression but increases tran...

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Guardado en:
Detalles Bibliográficos
Publicado: 2001
Materias:
CD25
IGF-1 mRNA
IGF-1 receptor
IL-2
MAPK
CD69 antigen
interleukin 2
interleukin 2 receptor
microtubule associated protein
protein kinase (calcium,calmodulin)
somatomedin C
somatomedin C receptor
transcription factor
transcription factor ea
transcription factor eb
unclassified drug
antigen expression
article
autocrine effect
controlled study
human
human cell
immunostimulation
insulin like activity
leukemia cell line
microtubule assembly
paracrine signaling
pathophysiology
priority journal
protein expression
protein modification
protein phosphorylation
protein synthesis
receptor down regulation
T lymphocyte activation
transcription regulation
Antigens, CD
Antigens, Differentiation, T-Lymphocyte
Down-Regulation
Humans
Immediate-Early Proteins
Insulin-Like Growth Factor I
Interleukin-2
Jurkat Cells
Kinetics
Lymphocyte Activation
Mitogen-Activated Protein Kinases
Receptor, IGF Type 1
Receptors, Interleukin-2
RNA, Messenger
T-Lymphocytes
Transcription, Genetic
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_07415400_v70_n2_p297_Brocardo
http://hdl.handle.net/20.500.12110/paper_07415400_v70_n2_p297_Brocardo
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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