Interferon-alpha 2b modulation of doxorubicin sensitivity in a multidrug resistant cell line

We evaluated the effect of interferon-alpha2b as a chemosensitiser on HCT-15 cell line in treatment with doxorubicin. Chemosensitivity was determined by [3H]-thymidine incorporation and tetrazolium assays. The levels of expression of P-glycoprotein, Bcl-2 oncoprotein and HLA-ABC complex, and cell cy...

Descripción completa

Guardado en:

Detalles Bibliográficos
Publicado:	2001
Materias:	Apoptosis Bcl-2 HLA-ABC Interferon-alpha 2b P-170 alpha2b interferon doxorubicin glycoprotein P HLA antigen protein bcl 2 tetrazolium thymidine tritium apoptosis article cancer cell culture cell cycle G2 phase cell viability concentration response controlled study drug potentiation flow cytometry gene expression human human cell multidrug resistance priority journal Adenocarcinoma Antineoplastic Agents Cell Cycle Cell Division Cell Survival Colonic Neoplasms Doxorubicin Drug Resistance, Multiple Drug Synergism G2 Phase Histocompatibility Antigens Class I HLA Antigens HLA-A Antigens HLA-C Antigens Humans Interferon Alfa-2b Membrane Proteins Mitosis Oncogene Protein v-cbl P-Glycoprotein Retroviridae Proteins, Oncogenic Tumor Cells, Cultured
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03929078_v20_n3_p393_Gritti http://hdl.handle.net/20.500.12110/paper_03929078_v20_n3_p393_Gritti
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

Ejemplares similares

Interferon-alpha 2b modulation of doxorubicin sensitivity in a multidrug resistant cell line
por: Gritti, M.F.L., et al.

Human M2 macrophages limit NK cell effector functions through secretion of TGF-b and engagement of CD85j
Publicado: (2018)

Human M2 macrophages limit NK cell effector functions through secretion of TGF-b and engagement of CD85j
por: Nuñez, S.Y., et al.

Monocyte-derived dendritic cells loaded with a mixture of apoptotic/ necrotic melanoma cells efficiently cross-present gp100 and MART-1 antigens to specific CD8+ T lymphocytes
por: von Euw, Erika María, et al.
Publicado: (2007)

Monocyte-derived dendritic cells loaded with a mixture of apoptotic/ necrotic melanoma cells efficiently cross-present gp100 and MART-1 antigens to specific CD8+ T lymphocytes
por: von Euw, E.M., et al.
Publicado: (2007)

Monocyte-derived dendritic cells loaded with a mixture of apoptotic/ necrotic melanoma cells efficiently cross-present gp100 and MART-1 antigens to specific CD8+ T lymphocytes
por: von Euw, E.M., et al.

Monocyte-derived dendritic cells loaded with a mixture of apoptotic/ necrotic melanoma cells efficiently cross-present gp100 and MART-1 antigens to specific CD8+ T lymphocytes
por: von Euw, E.M., et al.
Publicado: (2007)

HLA-G gene editing: a novel therapeutic alternative in cancer immunotherapy
por: Palma, María Belén, et al.
Publicado: (2021)

Regulation of HLA-DR antigen in monocytes from colorectal cancer patients by in vitro treatment with human recombinant interferon-γ
Publicado: (2000)

Regulation of HLA-DR antigen in monocytes from colorectal cancer patients by in vitro treatment with human recombinant interferon-γ
por: Novellino, P.S., et al.

Human granulosa cells express HLA-DR antigen and are capable of synthesizing interleukin-1
Publicado: (1995)

Human granulosa cells express HLA-DR antigen and are capable of synthesizing interleukin-1
por: Baranao, R.I., et al.

Human Natural Killer Cell Maturation Defect Supports In Vivo CD56bright to CD56dim Lineage Development
por: Domaica, Carolina Inés, et al.
Publicado: (2012)

Human Natural Killer Cell Maturation Defect Supports In Vivo CD56bright to CD56dim Lineage Development
por: Domaica, C.I., et al.
Publicado: (2012)

Human Natural Killer Cell Maturation Defect Supports In Vivo CD56bright to CD56dim Lineage Development
por: Domaica, C.I., et al.

Human Natural Killer Cell Maturation Defect Supports In Vivo CD56bright to CD56dim Lineage Development
por: Domaica, C.I., et al.
Publicado: (2012)

Effect of culture supernatants from two cancer cell lines on healthy donors' monocytes
Publicado: (1999)

Effect of culture supernatants from two cancer cell lines on healthy donors' monocytes
por: Novellino, P.S., et al.

Studies on Biosynthesis, Assembly and Expression of Human Major Transplantation Antigens
Publicado: (1980)

Studies on Biosynthesis, Assembly and Expression of Human Major Transplantation Antigens
por: ALGRANATI, I.D., et al.

Oral contraceptives suppress cell proliferation and enhance apoptosis of eutopic endometrial tissue from patients with endometriosis
Publicado: (2002)

Oral contraceptives suppress cell proliferation and enhance apoptosis of eutopic endometrial tissue from patients with endometriosis
por: Meresman, G.F., et al.

Influence of HLA-DR alleles on rheumatoid arthritis: Susceptibility and severity in Argentine patients
Publicado: (2001)

Influence of HLA-DR alleles on rheumatoid arthritis: Susceptibility and severity in Argentine patients
por: Citera, G., et al.

Programmed death (PD)-1:PD-ligand 1/PD-ligand 2 pathway inhibits T cell effector functions during human tuberculosis
Publicado: (2008)

Programmed death (PD)-1:PD-ligand 1/PD-ligand 2 pathway inhibits T cell effector functions during human tuberculosis
por: Jurado, J.O., et al.

Biologic, Immunocytochemical, and Cytogenetic Characterization of Two New Human Melanoma Cell Lines: IIB‐MEL‐LES and IIB‐MEL‐IAN
Publicado: (1995)

Biologic, Immunocytochemical, and Cytogenetic Characterization of Two New Human Melanoma Cell Lines: IIB‐MEL‐LES and IIB‐MEL‐IAN
por: KAIRIYAMA, C., et al.

Mechanisms involved in tissue-specific apopotosis regulated by glucocorticoids
por: Hoijman, Esteban, et al.
Publicado: (2008)

Mechanisms involved in tissue-specific apopotosis regulated by glucocorticoids
por: Viegas, L.R., et al.

Human hepatocytes apoptosis induced by replication of hepatitis B virus subgenotypes F1b and F4: Role of basal core promoter and preCore mutations
Publicado: (2018)

Human hepatocytes apoptosis induced by replication of hepatitis B virus subgenotypes F1b and F4: Role of basal core promoter and preCore mutations
por: Elizalde, M.M., et al.

Synergistic Antiproliferative Effects of a New Cucurbitacin B Derivative and Chemotherapy Drugs on Lung Cancer Cell Line A549
Publicado: (2015)

Synergistic Antiproliferative Effects of a New Cucurbitacin B Derivative and Chemotherapy Drugs on Lung Cancer Cell Line A549
por: Marostica, L.L., et al.

New treatment strategies based on apoptosis and viruses
por: Mersich, Susana E., et al.
Publicado: (2003)

New treatment strategies based on apoptosis and viruses
por: Mersich, S., et al.

Functional interaction between co-expressed MAGE-A proteins
por: Ladelfa, María Fátima
Publicado: (2017)

Functional interaction between co-expressed MAGE-A proteins
por: Laiseca, J.E., et al.

Proliferative inhibition and apoptotic mechanism on human non-small-cell lung cancer (A549 cells) of a novel cucurbitacin from Wilbrandia ebracteata cogn
Publicado: (2013)

Proliferative inhibition and apoptotic mechanism on human non-small-cell lung cancer (A549 cells) of a novel cucurbitacin from Wilbrandia ebracteata cogn
por: Silva, I.T., et al.