Acute administration of angiotensin II improves long-term habituation in the crab Chasmagnathus
A shadow moving overhead acts as a danger stimulus and elicits an escape response in the crab Chasmagnathus granulatus that habituates after 15 trials and for a long period. A shorter training of ten trials fails to induce long-term habituation; however, a good retention of the habituated response i...
Guardado en:
| Autores principales: | , , |
|---|---|
| Publicado: |
1995
|
| Materias: | |
| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03043940_v196_n2_p193_Delorenzi http://hdl.handle.net/20.500.12110/paper_03043940_v196_n2_p193_Delorenzi |
| Aporte de: |
| Sumario: | A shadow moving overhead acts as a danger stimulus and elicits an escape response in the crab Chasmagnathus granulatus that habituates after 15 trials and for a long period. A shorter training of ten trials fails to induce long-term habituation; however, a good retention of the habituated response is manifest after a 24-h interval when angiotensin II (AII) (10-6 M, 3 ng/g) is injected post-training. By contrast, no amnestic effect of AII was found even though high doses were administered. The facilitatory effect of AII is suppressed by saralasin (10-7 M, 0.3 ng/g), a specific angiotensin II receptor antagonist. Results are considered as suggesting that angiotensin on memory processes might have emerged early in evolution. © 1995 Elsevier Science Ireland Ltd. All rights reserved. |
|---|