Role of UTX in retinoic acid receptor-mediated gene regulation in leukemia

Human UTX, a member of the Jumonji C family of proteins, associates with mixed-lineage leukemia 3/4 complexes. Stimulation with retinoic acid leads to the recruitment of UTX-containing complexes to HOX genes, which results in demethylation of histone H3 lysine 27 and concomitant methylation of histo...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autor principal:	Rocha Viegas, Luciana
Publicado:	2014
Materias:	histone H3 lysine protein retinoic acid retinoic acid receptor alpha unclassified drug utx protein antineoplastic agent ASH2L protein, human DNA binding protein histone histone demethylase nuclear protein retinoic acid receptor transcription factor UTX protein, human Article cell differentiation cell maturation chromatin immunoprecipitation controlled study flow cytometry fluorescence activated cell sorting gene activation gene control gene expression gene overexpression gene silencing gene targeting genetic transcription genetic transfection human human cell immunoprecipitation in vivo study promoter region promyelocytic leukemia protein depletion protein interaction quantitative analysis retrovirus infection reverse transcription polymerase chain reaction transcription initiation U937 cell line article drug effect gene expression regulation genetics HEK293 cell line leukemia metabolism pathology tumor cell line Antineoplastic Agents Cell Differentiation Cell Line, Tumor DNA-Binding Proteins Gene Expression Regulation, Neoplastic Gene Knockdown Techniques HEK293 Cells Histone Demethylases Histones Humans Leukemia Nuclear Proteins Promoter Regions, Genetic Receptors, Retinoic Acid Transcription Factors Tretinoin U937 Cells
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_02707306_v34_n19_p3765_RochaViegas http://hdl.handle.net/20.500.12110/paper_02707306_v34_n19_p3765_RochaViegas
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

Ejemplares similares

Role of UTX in retinoic acid receptor-mediated gene regulation in leukemia
por: Rocha-Viegas, L., et al.

Mapping the Dynamics of the Glucocorticoid Receptor within the Nuclear Landscape
por: Stortz, M., et al.

Mapping the Dynamics of the Glucocorticoid Receptor within the Nuclear Landscape
Publicado: (2017)

NF-κB transcriptional activity is modulated by FK506-Binding proteins FKBP51 and FKBP52:A role for peptidyl-prolyl isomerase activity
por: Erlejman, A.G., et al.

NF-κB transcriptional activity is modulated by FK506-Binding proteins FKBP51 and FKBP52:A role for peptidyl-prolyl isomerase activity
por: Fontana, Vanina Andrea
Publicado: (2014)

Modulation of chromatin modifying factors' gene expression in embryonic and induced pluripotent stem cells
por: Luzzani, C., et al.

Modulation of chromatin modifying factors' gene expression in embryonic and induced pluripotent stem cells
por: Luzzani, Carlos Daniel, et al.
Publicado: (2011)

MageA2 restrains cellular senescence by targeting the function of PMLIV/p53 axis at the PML-NBs
por: Peche, L.Y., et al.
Publicado: (2012)

MageA2 restrains cellular senescence by targeting the function of PMLIV/p53 axis at the PML-NBs
por: Peche, L.Y., et al.

MageA2 restrains cellular senescence by targeting the function of PMLIV/p53 axis at the PML-NBs
por: Peche, L.Y., et al.
Publicado: (2012)

MageA2 restrains cellular senescence by targeting the function of PMLIV/p53 axis at the PML-NBs
por: Ladelfa, María Fátima, et al.
Publicado: (2012)

Glucocorticoids repress bcl-X expression in lymphoid cells by recruiting STAT5B to the P4 promoter
por: Rocha-Viegas, L., et al.
Publicado: (2006)

Glucocorticoids repress bcl-X expression in lymphoid cells by recruiting STAT5B to the P4 promoter
por: Rocha-Viegas, L., et al.
Publicado: (2006)

Glucocorticoids repress bcl-X expression in lymphoid cells by recruiting STAT5B to the P4 promoter
por: Rocha-Viegas, L., et al.

Glucocorticoids repress bcl-X expression in lymphoid cells by recruiting STAT5B to the P4 promoter
por: Rocha Viegas, Luciana, et al.
Publicado: (2006)

Human MageB2 protein expression enhances E2F transcriptional activity, cell proliferation, and resistance to ribotoxic stress
por: Peche, L.Y., et al.

Human MageB2 protein expression enhances E2F transcriptional activity, cell proliferation, and resistance to ribotoxic stress
por: Ladelfa, María Fátima
Publicado: (2015)

Mutations in CDON, encoding a hedgehog receptor, result in holoprosencephaly and defective interactions with other hedgehog receptors
por: Bae, G.-U., et al.

Mutations in CDON, encoding a hedgehog receptor, result in holoprosencephaly and defective interactions with other hedgehog receptors
Publicado: (2011)

Progesterone receptor induces bcl-x expression through intragenic binding sites favoring RNA polymerase II elongation
por: Bertucci, P.Y., et al.

Progesterone receptor induces bcl-x expression through intragenic binding sites favoring RNA polymerase II elongation
por: Bertucci, Paola Yanina, et al.
Publicado: (2013)

RSUME enhances glucocorticoid receptor SUMOylation and transcriptional activity
por: Druker, J., et al.

RSUME enhances glucocorticoid receptor SUMOylation and transcriptional activity
por: Druker, Jimena Paola, et al.
Publicado: (2013)

Functional interaction between co-expressed MAGE-A proteins
por: Laiseca, J.E., et al.

Functional interaction between co-expressed MAGE-A proteins
por: Ladelfa, María Fátima
Publicado: (2017)

Differential antiapoptotic effect of erythropoietin on undifferentiated and retinoic acid-differentiated SH-SY5Y cells
por: Wenker, S.D., et al.

Differential antiapoptotic effect of erythropoietin on undifferentiated and retinoic acid-differentiated SH-SY5Y cells
Publicado: (2010)

Gatekeepers of pancreas: TEAD and YAP
por: Rodríguez-Seguí, S.A., et al.

Gatekeepers of pancreas: TEAD and YAP
por: Rodriguez Segui, Santiago Andres
Publicado: (2015)

p8/nupr1 regulates DNA-repair activity after double-strand gamma irradiation-induced DNA damage
por: Gironella, M., et al.

p8/nupr1 regulates DNA-repair activity after double-strand gamma irradiation-induced DNA damage
Publicado: (2009)

The estrogen receptor alpha nuclear localization sequence is critical for fulvestrant-induced degradation of the receptor
por: Casa, A.J., et al.

The estrogen receptor alpha nuclear localization sequence is critical for fulvestrant-induced degradation of the receptor
Publicado: (2015)

Mdm2 promotes Cdc25C protein degradation and delays cell cycle progression through the G2/M phase
por: Giono, L.E., et al.

Mdm2 promotes Cdc25C protein degradation and delays cell cycle progression through the G2/M phase
Publicado: (2017)

The increase in cytosolic levels of protein kinase C precedes the growth factor requirements during the transition stem cells to differentiated progeny in the MCF-7 breast tumor cells.
por: Gomez, M.L., et al.

The increase in cytosolic levels of protein kinase C precedes the growth factor requirements during the transition stem cells to differentiated progeny in the MCF-7 breast tumor cells.
por: Gómez, María Laura, et al.
Publicado: (1993)

Gene expression regulation by heat-shock proteins: the cardinal roles of HSF1 and Hsp90
por: Mazaira, G.I., et al.

Gene expression regulation by heat-shock proteins: the cardinal roles of HSF1 and Hsp90
Publicado: (2018)

Steroid receptor coupling becomes nuclear
por: Galigniana, M.D.