Relative biological effectiveness measurements of low energy proton and lithium beams on tumor cells

External proton and 6,7Li beams, of energies around 24 and 48 MeV respectively, were produced and characterized dosimetrically at the Tandem accelerator TANDAR in Buenos Aires and used for radiobiology studies on tumor and normal cell cultures. The beam monitoring instrumentation of a dedicated beam...

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Autores principales:	Schuff, Juan Alberto, Policastro, Lucía Laura, Durán, Hebe Alicia, Kreiner, Andrés Juan, Molinari de Rey, Beatriz, Burlon, Alejandro, Debray, Mario Ernesto, Somacal, Héctor R., Saint Martín, María Laura Gisela, O'Connor, Silvia E., Davidson, Jorge, Davidson, Miguel, Caneva, Sandra, Palmieri, Mónica Alejandra
Publicado:	2002
Materias:	6,7Li ions Cells Dosimetry Instrumentation Protons RBE Biological radiation effects Cell culture Lithium Particle accelerators Radiotherapy Tumors Radiobiology Proton beams
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0168583X_v187_n3_p345_Schuff http://hdl.handle.net/20.500.12110/paper_0168583X_v187_n3_p345_Schuff
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	paper:paper_0168583X_v187_n3_p345_Schuff
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spelling	paper:paper_0168583X_v187_n3_p345_Schuff2023-06-08T15:17:47Z Relative biological effectiveness measurements of low energy proton and lithium beams on tumor cells Schuff, Juan Alberto Policastro, Lucía Laura Durán, Hebe Alicia Kreiner, Andrés Juan Molinari de Rey, Beatriz Burlon, Alejandro Debray, Mario Ernesto Somacal, Héctor R. Saint Martín, María Laura Gisela O'Connor, Silvia E. Davidson, Jorge Davidson, Miguel Caneva, Sandra Palmieri, Mónica Alejandra 6,7Li ions Cells Dosimetry Instrumentation Protons RBE Biological radiation effects Cell culture Dosimetry Lithium Particle accelerators Radiotherapy Tumors Radiobiology Proton beams External proton and 6,7Li beams, of energies around 24 and 48 MeV respectively, were produced and characterized dosimetrically at the Tandem accelerator TANDAR in Buenos Aires and used for radiobiology studies on tumor and normal cell cultures. The beam monitoring instrumentation of a dedicated beam line is discussed. Relative biological effectiveness (RBE) values (at 10% survival) have been measured as functions of projectile energy (0-21 MeV) for protons and 6,7Li ions for different tumor (PDV, PDVC57) and reference cell lines (V79). The RBE values for these cell lines have been determined here for the first time but are similar to those reported in the literature for other cell lines. © 2002 Elsevier Science B.V. All rights reserved. Fil:Schuff, J.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Policastro, L. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Durán, H. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Kreiner, A.J Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Molinari, B.L. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Burlón, A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Debray, M.E. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Somacal, H. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Saint-Martin, G. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:O'Connor, S. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Davidson, J. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Davidson, M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Cáneva, S. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Palmieri, M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 2002 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0168583X_v187_n3_p345_Schuff http://hdl.handle.net/20.500.12110/paper_0168583X_v187_n3_p345_Schuff
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	6,7Li ions Cells Dosimetry Instrumentation Protons RBE Biological radiation effects Cell culture Dosimetry Lithium Particle accelerators Radiotherapy Tumors Radiobiology Proton beams
spellingShingle	6,7Li ions Cells Dosimetry Instrumentation Protons RBE Biological radiation effects Cell culture Dosimetry Lithium Particle accelerators Radiotherapy Tumors Radiobiology Proton beams Schuff, Juan Alberto Policastro, Lucía Laura Durán, Hebe Alicia Kreiner, Andrés Juan Molinari de Rey, Beatriz Burlon, Alejandro Debray, Mario Ernesto Somacal, Héctor R. Saint Martín, María Laura Gisela O'Connor, Silvia E. Davidson, Jorge Davidson, Miguel Caneva, Sandra Palmieri, Mónica Alejandra Relative biological effectiveness measurements of low energy proton and lithium beams on tumor cells
topic_facet	6,7Li ions Cells Dosimetry Instrumentation Protons RBE Biological radiation effects Cell culture Dosimetry Lithium Particle accelerators Radiotherapy Tumors Radiobiology Proton beams
description	External proton and 6,7Li beams, of energies around 24 and 48 MeV respectively, were produced and characterized dosimetrically at the Tandem accelerator TANDAR in Buenos Aires and used for radiobiology studies on tumor and normal cell cultures. The beam monitoring instrumentation of a dedicated beam line is discussed. Relative biological effectiveness (RBE) values (at 10% survival) have been measured as functions of projectile energy (0-21 MeV) for protons and 6,7Li ions for different tumor (PDV, PDVC57) and reference cell lines (V79). The RBE values for these cell lines have been determined here for the first time but are similar to those reported in the literature for other cell lines. © 2002 Elsevier Science B.V. All rights reserved.
author	Schuff, Juan Alberto Policastro, Lucía Laura Durán, Hebe Alicia Kreiner, Andrés Juan Molinari de Rey, Beatriz Burlon, Alejandro Debray, Mario Ernesto Somacal, Héctor R. Saint Martín, María Laura Gisela O'Connor, Silvia E. Davidson, Jorge Davidson, Miguel Caneva, Sandra Palmieri, Mónica Alejandra
author_facet	Schuff, Juan Alberto Policastro, Lucía Laura Durán, Hebe Alicia Kreiner, Andrés Juan Molinari de Rey, Beatriz Burlon, Alejandro Debray, Mario Ernesto Somacal, Héctor R. Saint Martín, María Laura Gisela O'Connor, Silvia E. Davidson, Jorge Davidson, Miguel Caneva, Sandra Palmieri, Mónica Alejandra
author_sort	Schuff, Juan Alberto
title	Relative biological effectiveness measurements of low energy proton and lithium beams on tumor cells
title_short	Relative biological effectiveness measurements of low energy proton and lithium beams on tumor cells
title_full	Relative biological effectiveness measurements of low energy proton and lithium beams on tumor cells
title_fullStr	Relative biological effectiveness measurements of low energy proton and lithium beams on tumor cells
title_full_unstemmed	Relative biological effectiveness measurements of low energy proton and lithium beams on tumor cells
title_sort	relative biological effectiveness measurements of low energy proton and lithium beams on tumor cells
publishDate	2002
url	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0168583X_v187_n3_p345_Schuff http://hdl.handle.net/20.500.12110/paper_0168583X_v187_n3_p345_Schuff
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Relative biological effectiveness measurements of low energy proton and lithium beams on tumor cells

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