Heparin and Concanavalin A interaction as a model for studying the mechanism of the anticoagulant activity

A systematic study of the role of the Ca2+ and Mn2+ ions on the interaction between heparin and Concanavalin A was carried out. The protein was demetallized, and complex formation was followed by a light scattering assay. In the absence of ions no visible interaction was detected. Maximum activity w...

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Detalles Bibliográficos
Autor principal:	Recondo, Eduardo Francisco
Publicado:	1989
Materias:	calcium concanavalin a heparin magnesium anticoagulation methodology model nonbiological model nonhuman priority journal Binding, Competitive Blood Coagulation Calcium Concanavalin A Drug Interactions Heparin Kinetics Light Manganese Models, Biological Protein Conformation Scattering, Radiation Spectrophotometry Support, Non-U.S. Gov't
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00493848_v54_n3_p237_Monge http://hdl.handle.net/20.500.12110/paper_00493848_v54_n3_p237_Monge
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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