NF-κB transcriptional activity is modulated by FK506-Binding proteins FKBP51 and FKBP52:A role for peptidyl-prolyl isomerase activity

Hsp90 binding immunophilins FKBP51 and FKBP52 modulate steroid receptor trafficking and hormone-dependent biological responses. With the purpose to expand this model to other nuclear factors that are also subject to nuclear-cytoplasmic shuttling, we analyzed whether these immunophilins modulate NF-κ...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autor principal: Fontana, Vanina Andrea
Publicado: 2014
Materias:
fk 506 binding protein
glucocorticoid receptor
protein binding
RELA protein, human
tacrolimus binding protein 4
tacrolimus binding protein 5
transcription factor RelA
active transport
animal
cell nucleus
genetic transcription
HEK293 cell line
human
metabolism
physiology
promoter region
protein domain
rat
transcription initiation
Active Transport, Cell Nucleus
Animals
Cell Nucleus
HEK293 Cells
Humans
Promoter Regions, Genetic
Protein Binding
Protein Interaction Domains and Motifs
Rats
Receptors, Glucocorticoid
Tacrolimus Binding Proteins
Transcription Factor RelA
Transcription, Genetic
Transcriptional Activation
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00219258_v289_n38_p26263_Erlejman
http://hdl.handle.net/20.500.12110/paper_00219258_v289_n38_p26263_Erlejman
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

Ejemplares similares

Ejemplares similares