Activation of JNK by Epac Is Independent of Its Activity as a Rap Guanine Nucleotide Exchanger

Guanine nucleotide exchange factors (GEFs) and their associated GTP-binding proteins (G-proteins) are key regulatory elements in the signal transduction machinery that relays information from the extracellular environment into specific intracellular responses. Among them, the MAPK cascades represent...

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Detalles Bibliográficos
Publicado:	2003
Materias:	Catalysis Cells Proteins Mutants Biochemistry guanine nucleotide exchange factor Janus kinase Rap protein complementary DNA DNA glutathione transferase mitogen activated protein kinase mitogen activated protein kinase 1 mitogen activated protein kinase 3 mitogen activated protein kinase kinase mitogen activated protein kinase kinase 4 mitogen activated protein kinase p38 RAPGEF3 protein, human stress activated protein kinase Vpr protein animal cell article catalysis cell proliferation deletion mutant enzyme activation enzyme activity enzyme specificity genetic analysis nonhuman priority journal protein domain protein family protein stability second messenger signal transduction cell line dominant gene gene deletion genetic transfection human metabolism mutation plasmid protein binding protein motif protein tertiary structure time Western blotting Animalia Janus Amino Acid Motifs Blotting, Western Cell Line DNA, Complementary Enzyme Activation Gene Deletion Gene Products, vpr Genes, Dominant Glutathione Transferase Guanine Nucleotide Exchange Factors Humans JNK Mitogen-Activated Protein Kinases MAP Kinase Kinase 4 Mitogen-Activated Protein Kinase 1 Mitogen-Activated Protein Kinase 3 Mitogen-Activated Protein Kinase Kinases Mitogen-Activated Protein Kinases Mutation p38 Mitogen-Activated Protein Kinases Plasmids Protein Binding Protein Structure, Tertiary Signal Transduction Time Factors Transfection
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00219258_v278_n36_p33738_Hochbaum http://hdl.handle.net/20.500.12110/paper_00219258_v278_n36_p33738_Hochbaum
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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