A biphasic effect of estradiol on serotonin metabolism in rat pineal organ cultures

Physiological amounts of estradiol (1 nM) significantly increased serotonin, conversion to melatonin and 5-methoxytryptophol by rat pineal glands in organ culture whereas larger, pharmacological, doses (i.e. 1000 nM) impaired it significantly. The stimulatory but not the inhibitory effect of estradi...

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Detalles Bibliográficos
Publicado:	1981
Materias:	5 methoxytryptophol estradiol melatonin puromycin radioisotope serotonin animal experiment drug metabolism endocrine system in vitro study organ culture pineal body rat Animal Dose-Response Relationship, Drug Estradiol Organ Culture Pineal Gland Puromycin Rats Serotonin Support, Non-U.S. Gov't
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00144754_v37_n2_p203_Cardinali http://hdl.handle.net/20.500.12110/paper_00144754_v37_n2_p203_Cardinali
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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