Regulation of placental leptin expression by cyclic adenosine 5′-monophosphate involves cross talk between protein kinase A and mitogen-activated protein kinase signaling pathways

Leptin, a 16-kDa protein mainly produced by adipose tissue, has been involved in the control of energy balance through its hypothalamic receptor. However, pleiotropic effects of leptin have been identified in reproduction and pregnancy, particularly in placenta, where it was found to be expressed. I...

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Detalles Bibliográficos
Autores principales:	Maymó, Julieta L., Calvo, Juan Carlos, Varone, Cecilia Laura
Publicado:	2010
Materias:	2 (2 amino 3 methoxyphenyl)chromone adenylate cyclase bucladesine cyclic AMP cyclic AMP dependent protein kinase cyclic AMP responsive element binding protein leptin mitogen activated protein kinase 1 mitogen activated protein kinase 3 article concentration response controlled study enzyme active site enzyme inhibition explant gene activity hormone release human human cell human tissue physiological process placenta plasmid priority journal promoter region protein phosphorylation regulatory mechanism reporter gene reverse transcription polymerase chain reaction signal transduction transient transfection trophoblast upregulation Western blotting
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00137227_v151_n8_p3738_Maymo http://hdl.handle.net/20.500.12110/paper_00137227_v151_n8_p3738_Maymo
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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