The FIP-1 like polyadenylation factor in trypanosomes and the structural basis for its interaction with CPSF30

In trypanosomes transcription is polycistronic and individual mRNAs are generated by a trans-splicing/polyadenylation coupled reaction. We identified a divergent trypanosome FIP1-like, a factor required for mRNA 3′ end formation from yeasts to human. Here we showed that it is a nuclear protein with...

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Detalles Bibliográficos
Autores principales: Bercovich, Natalia, Vazquez, Martín Pablo
Publicado: 2009
Materias:
Drug target
mRNA processing
Polyadenylation factors
Protein interactions
Trypanosome diseases
amino acid
cleavage and polyadenylation specificity factor
cpsf30 protein
fip1 protein
nuclear protein
protein
unclassified drug
amino acid blood level
article
cell surface
controlled study
human
human cell
nonhuman
parasite viability
polyadenylation
priority journal
protein interaction
Trypanosoma
Amino Acid Sequence
Animals
Cleavage And Polyadenylation Specificity Factor
Molecular Sequence Data
mRNA Cleavage and Polyadenylation Factors
Polyadenylation
Trypanosoma brucei brucei
Trypanosoma cruzi
Two-Hybrid System Techniques
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0006291X_v380_n4_p850_Bercovich
http://hdl.handle.net/20.500.12110/paper_0006291X_v380_n4_p850_Bercovich
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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