The expression of the mitochondrial gene MT-ND4 is downregulated in cystic fibrosis

Cystic fibrosis (CF) is a disease produced by mutations in the CFTR channel. We have previously reported that the CFTR chloride transport activity indirectly regulates the differential expression of several genes, including SRC and MUC1. Here we report that MT-ND4, a mitochondrial gene encoding a su...

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Detalles Bibliográficos
Autores principales: Valdivieso, Angel Gabriel, Marcucci, Florencia, Taminelli, Guillermo Luis, Dankert, Marcelo Alberto, Santa Coloma, Tomás Antonio
Publicado: 2007
Materias:
CFDE
CFTR
CFTR(inh)-172
Cystic fibrosis
Glibenclamide
Mitochondria
Mitochondrial expressed genes
MT-ND4
glibenclamide
reduced nicotinamide adenine dinucleotide dehydrogenase (ubiquinone)
transmembrane conductance regulator
article
controlled study
cystic fibrosis
histopathology
human
human cell
human tissue
in situ hybridization
mitochondrial gene
mt nd4 gene
nucleotide sequence
priority journal
protein expression
Base Sequence
Benzoic Acids
Cell Line
Cystic Fibrosis
Cystic Fibrosis Transmembrane Conductance Regulator
Down-Regulation
Gene Expression
Glyburide
Humans
In Situ Hybridization
Lung
Molecular Sequence Data
NADH Dehydrogenase
Thiazolidines
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0006291X_v356_n3_p805_Valdivieso
http://hdl.handle.net/20.500.12110/paper_0006291X_v356_n3_p805_Valdivieso
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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