The inhibition of insect chitin synthesis by tunicamycin

The conversion of [14C]-labeled glucosamine to [14C]-labeled insect chitin was inhibited by tunicamycin, a nucleoside antibiotic which specifically blocks the biosynthesis of dolichyl diphosphate N-Acetylglucosamine. A method of short-term culturing is described for the analysis of chitin and glycon...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado: 1982
Materias:
chitin
polyoxin d
tunicamycin
drug synthesis
glucosamine c 14
glucose c 14
nonhuman
Animal
Carbon Radioisotopes
Chitin
Glucosamine
Hemiptera
Kinetics
Support, Non-U.S. Gov't
Tunicamycin
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0006291X_v105_n1_p312_QuesadaAllue
http://hdl.handle.net/20.500.12110/paper_0006291X_v105_n1_p312_QuesadaAllue
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
Descripción
Sumario:The conversion of [14C]-labeled glucosamine to [14C]-labeled insect chitin was inhibited by tunicamycin, a nucleoside antibiotic which specifically blocks the biosynthesis of dolichyl diphosphate N-Acetylglucosamine. A method of short-term culturing is described for the analysis of chitin and glyconjugates biosynthesis by epidermal tissue of Triatoma infestans. © 1982 Academic Press, Inc.

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