Emerging insights into hypothalamic-pituitary- gonadal axis regulation and interaction with stress signalling.

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ARTÍCULO PUBLICADO EN REVISTA EXTERNA.Reproduction and fertility are regulated via hormones of the hypothalamic-pituitary-gonadal (HPG) axis. Control of this reproductive axis occurs at all levels, including the brain and pituitary, and allows for the promotion or inhibition of gonadal sex steroid s...

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Autores principales: Acevedo-Rodríguez, Alexandra, Kauffman, Alexander, Cherrington, Brian, Borges, Cibele, Roepke, Troy, Laconi, Myriam
Formato: Artículo Científico
Lenguaje:Inglés
Publicado: Comité editorial Journal of Neuroendocrinology 2020
Materias:
GnRH
Kisspeptin
Oestradiol
Reproduction
Stress
Acceso en línea:http://repositorio.umaza.edu.ar//handle/00261/1821
https://pubmed.ncbi.nlm.nih.gov/29524268/
Aporte de:
UMAZA Digital (Universidad MAZA - Mendoza) de Universidad Juan Agustín MAZA
id I56-R16200261-1821
record_format dspace
institution Universidad Juan Agustín MAZA
institution_str I-56
repository_str R-162
collection UMAZA Digital (Universidad MAZA - Mendoza)
language Inglés
orig_language_str_mv eng
topic GnRH
Kisspeptin
Oestradiol
Reproduction
Stress
spellingShingle GnRH
Kisspeptin
Oestradiol
Reproduction
Stress
Acevedo-Rodríguez, Alexandra
Kauffman, Alexander
Cherrington, Brian
Borges, Cibele
Roepke, Troy
Laconi, Myriam
Emerging insights into hypothalamic-pituitary- gonadal axis regulation and interaction with stress signalling.
description ARTÍCULO PUBLICADO EN REVISTA EXTERNA.Reproduction and fertility are regulated via hormones of the hypothalamic-pituitary-gonadal (HPG) axis. Control of this reproductive axis occurs at all levels, including the brain and pituitary, and allows for the promotion or inhibition of gonadal sex steroid secretion and function. In addition to guiding proper gonadal development and function, gonadal sex steroids also act in negative-and positive-feedback loops to regulate reproductive circuitry in the brain, including kisspeptin neurones, thereby modulating overall HPG axis status. Additional regulation is also provided by sex steroids made within the brain, including neuroprogestins. Furthermore, because reproduction and survival need to be coordinated and balanced, the HPG axis is able to modulate (and be modulated by) stress hormone signalling, including cortiscosterone, from the hypothalamic-pituitary- adrenal (HPA) axis. This review covers recent data related to the neural, hormonal and stress regulation of the HPG axis and emerging interactions between the HPG and HPA axes, focusing on actions at the level of the brain and pituitary. Sitio de la revista: https://pubmed.ncbi.nlm.nih.gov/29524268/
format Artículo Científico
author Acevedo-Rodríguez, Alexandra
Kauffman, Alexander
Cherrington, Brian
Borges, Cibele
Roepke, Troy
Laconi, Myriam
author_facet Acevedo-Rodríguez, Alexandra
Kauffman, Alexander
Cherrington, Brian
Borges, Cibele
Roepke, Troy
Laconi, Myriam
author_sort Acevedo-Rodríguez, Alexandra
title Emerging insights into hypothalamic-pituitary- gonadal axis regulation and interaction with stress signalling.
title_short Emerging insights into hypothalamic-pituitary- gonadal axis regulation and interaction with stress signalling.
title_full Emerging insights into hypothalamic-pituitary- gonadal axis regulation and interaction with stress signalling.
title_fullStr Emerging insights into hypothalamic-pituitary- gonadal axis regulation and interaction with stress signalling.
title_full_unstemmed Emerging insights into hypothalamic-pituitary- gonadal axis regulation and interaction with stress signalling.
title_sort emerging insights into hypothalamic-pituitary- gonadal axis regulation and interaction with stress signalling.
publisher Comité editorial Journal of Neuroendocrinology
publishDate 2020
url http://repositorio.umaza.edu.ar//handle/00261/1821
https://pubmed.ncbi.nlm.nih.gov/29524268/
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