A Single Nucleotide Polymorphism Translates into a Radical Amino Acid Substitution at the Ligand-Binding Site in Fasciola hepatica Carboxylesterase B

Fasciola hepatica anthelmintic resistance may be associated with the catalytic activity of xenobiotic metabolizing enzymes. The gene expression of one of these enzymes, identified as car boxylesterase B (CestB), was previously described as inducible in adult parasites under anthelmintic treatment an...

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Detalles Bibliográficos
Autores principales: Miranda-Miranda, Estefan, Scarcella, Silvana, Reynaud, Enrique, Narváez-Padilla, Verónica, Neira, Gisela, Mera y Sierra, Roberto, Aguilar-Díaz, Hugo, Cossio-Bayugar, Raquel
Formato: Artículo Científico
Lenguaje:Inglés
Publicado: Comite editorial GENES 2022
Materias:
SNTP
Carboxylesterase
Amino acid substitution
Fasciola hepatica
Anthelmintic resistance
Bioinformatics
Acceso en línea:https://repositorio.umaza.edu.ar/handle/00261/3093
Aporte de:
UMAZA Digital (Universidad MAZA - Mendoza) de Universidad Juan Agustín MAZA

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