Validation of PRISM and PIM2 scores of mortality in a pediatric intensive care unit in Cordoba [Validación de los puntajes de mortalidad PRISM y PIM2 en una unidad de cuidados intensivos pediátricos de Córdoba]

Introduction. Pediatric Index of Mortality 2 (PIM2) and Pediatric Risk of Mortality (PRISM) are scoring systems to predict mortality likehood; thus, it is necessary to validate such predictors in Pediatric Intensive Care Units' population. Objective. To assess the validity of PRISM and PIM2 mod...

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Autores principales: Canonero, Ivana, Figueroa, Ana Cristina, Cacciamano, Ariel, Olivier, Eva, Cuestas, Eduardo José
Formato: Artículo PeerReviewed
Lenguaje:Español
Publicado: Sociedad Argentina de Pediatria 2010
Materias:
RJ Pediatría
Acceso en línea:http://pa.bibdigital.ucc.edu.ar/4974/1/A_Canonero.pdf
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Producción Académica Universidad Católica de Córdoba (UCCor) de Universidad Católica de Córdoba
id I38-R144-4974
record_format dspace
spelling I38-R144-49742025-11-03T13:58:47Z http://pa.bibdigital.ucc.edu.ar/4974/ Validation of PRISM and PIM2 scores of mortality in a pediatric intensive care unit in Cordoba [Validación de los puntajes de mortalidad PRISM y PIM2 en una unidad de cuidados intensivos pediátricos de Córdoba] Canonero, Ivana Figueroa, Ana Cristina Cacciamano, Ariel Olivier, Eva Cuestas, Eduardo José RJ Pediatría Introduction. Pediatric Index of Mortality 2 (PIM2) and Pediatric Risk of Mortality (PRISM) are scoring systems to predict mortality likehood; thus, it is necessary to validate such predictors in Pediatric Intensive Care Units' population. Objective. To assess the validity of PRISM and PIM2 models of Mortality in Pediatrics Intensive Care Units at Hospital Infantil de Córdoba (PICUHI). Population, material and methods. 435 critically ill admitted patients were retrospectively analized in PICUHI from January 1st 2008 to January 31st 2008; 416 were included in the study, ruling out elective admitted patients with less than 12 hour at PICU length stay. There were no deaths in this Group. Original equations for each models, were used. Calibration was performed (p> 0.05) using Hosmer-Lemeshow (HL) goodness-of-fit tests. Scores were assessed through Standardized Mortality Ratio (SMR) and discrimination between patients alived and dead, was estimated calculating the area under ROC curve. Results. 416 admitted patients were included, (55.04%) were male 55.04%, median age was 3 years (1 month-17 years), with a median of 2 (1-76) admitted days in PICU. Mortality was 6.66%. PIM2 had an area under ROC curve of 0.88 (CI 95% 0.82-0.95) and PRIMS: 0.85 (CI 95% 0.78-0.92), with p 0.3570 value. HL calibration for PRISM was: x2 5.93 (p 0.54), and PIM2 was: x2 14.19 (p 0.07). PRISM, Standardized Mortality Ratio (SMR) was: 1.00 (CI 95% 0.50-1.50) and PIM2 was 1.00 (CI 95% 0.55-1.55). Conclusions. Both scores discriminated and calibrated well as the p-value of the HL test, althougt the analysis of the HL table appears inadequate to PIM2 calibration, in terms of severity-adjusted mortality. Sociedad Argentina de Pediatria 2010-12-31 Artículo PeerReviewed application/pdf spa http://pa.bibdigital.ucc.edu.ar/4974/1/A_Canonero.pdf Canonero, Ivana, Figueroa, Ana Cristina ORCID: https://orcid.org/0000-0002-9567-4192 <https://orcid.org/0000-0002-9567-4192>, Cacciamano, Ariel, Olivier, Eva and Cuestas, Eduardo José ORCID: https://orcid.org/0000-0001-9528-5747 <https://orcid.org/0000-0001-9528-5747> (2010) Validation of PRISM and PIM2 scores of mortality in a pediatric intensive care unit in Cordoba [Validación de los puntajes de mortalidad PRISM y PIM2 en una unidad de cuidados intensivos pediátricos de Córdoba]. Archivos Argentinos de Pediatria, 108 (5). pp. 427-433. ISSN 0325-0075
institution Universidad Católica de Córdoba
institution_str I-38
repository_str R-144
collection Producción Académica Universidad Católica de Córdoba (UCCor)
language Español
orig_language_str_mv spa
topic RJ Pediatría
spellingShingle RJ Pediatría
Canonero, Ivana
Figueroa, Ana Cristina
Cacciamano, Ariel
Olivier, Eva
Cuestas, Eduardo José
Validation of PRISM and PIM2 scores of mortality in a pediatric intensive care unit in Cordoba [Validación de los puntajes de mortalidad PRISM y PIM2 en una unidad de cuidados intensivos pediátricos de Córdoba]
topic_facet RJ Pediatría
description Introduction. Pediatric Index of Mortality 2 (PIM2) and Pediatric Risk of Mortality (PRISM) are scoring systems to predict mortality likehood; thus, it is necessary to validate such predictors in Pediatric Intensive Care Units' population. Objective. To assess the validity of PRISM and PIM2 models of Mortality in Pediatrics Intensive Care Units at Hospital Infantil de Córdoba (PICUHI). Population, material and methods. 435 critically ill admitted patients were retrospectively analized in PICUHI from January 1st 2008 to January 31st 2008; 416 were included in the study, ruling out elective admitted patients with less than 12 hour at PICU length stay. There were no deaths in this Group. Original equations for each models, were used. Calibration was performed (p> 0.05) using Hosmer-Lemeshow (HL) goodness-of-fit tests. Scores were assessed through Standardized Mortality Ratio (SMR) and discrimination between patients alived and dead, was estimated calculating the area under ROC curve. Results. 416 admitted patients were included, (55.04%) were male 55.04%, median age was 3 years (1 month-17 years), with a median of 2 (1-76) admitted days in PICU. Mortality was 6.66%. PIM2 had an area under ROC curve of 0.88 (CI 95% 0.82-0.95) and PRIMS: 0.85 (CI 95% 0.78-0.92), with p 0.3570 value. HL calibration for PRISM was: x2 5.93 (p 0.54), and PIM2 was: x2 14.19 (p 0.07). PRISM, Standardized Mortality Ratio (SMR) was: 1.00 (CI 95% 0.50-1.50) and PIM2 was 1.00 (CI 95% 0.55-1.55). Conclusions. Both scores discriminated and calibrated well as the p-value of the HL test, althougt the analysis of the HL table appears inadequate to PIM2 calibration, in terms of severity-adjusted mortality.
format Artículo
PeerReviewed
author Canonero, Ivana
Figueroa, Ana Cristina
Cacciamano, Ariel
Olivier, Eva
Cuestas, Eduardo José
author_facet Canonero, Ivana
Figueroa, Ana Cristina
Cacciamano, Ariel
Olivier, Eva
Cuestas, Eduardo José
author_sort Canonero, Ivana
title Validation of PRISM and PIM2 scores of mortality in a pediatric intensive care unit in Cordoba [Validación de los puntajes de mortalidad PRISM y PIM2 en una unidad de cuidados intensivos pediátricos de Córdoba]
title_short Validation of PRISM and PIM2 scores of mortality in a pediatric intensive care unit in Cordoba [Validación de los puntajes de mortalidad PRISM y PIM2 en una unidad de cuidados intensivos pediátricos de Córdoba]
title_full Validation of PRISM and PIM2 scores of mortality in a pediatric intensive care unit in Cordoba [Validación de los puntajes de mortalidad PRISM y PIM2 en una unidad de cuidados intensivos pediátricos de Córdoba]
title_fullStr Validation of PRISM and PIM2 scores of mortality in a pediatric intensive care unit in Cordoba [Validación de los puntajes de mortalidad PRISM y PIM2 en una unidad de cuidados intensivos pediátricos de Córdoba]
title_full_unstemmed Validation of PRISM and PIM2 scores of mortality in a pediatric intensive care unit in Cordoba [Validación de los puntajes de mortalidad PRISM y PIM2 en una unidad de cuidados intensivos pediátricos de Córdoba]
title_sort validation of prism and pim2 scores of mortality in a pediatric intensive care unit in cordoba [validación de los puntajes de mortalidad prism y pim2 en una unidad de cuidados intensivos pediátricos de córdoba]
publisher Sociedad Argentina de Pediatria
publishDate 2010
url http://pa.bibdigital.ucc.edu.ar/4974/1/A_Canonero.pdf
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