Impact of environmental tobacco smoke and active tobacco smoking on the development and outcomes of asthma and rhinitis
Several deleterious effects have been described in asthma because of smoking: accelerated decline in lung function, more severe symptoms, impairment in quality of life and diminished therapeutic response to steroids. The harmful effect of tobacco smoking is not only on asthma but also on rhinitis pl...
Guardado en:
| Autores principales: | , , , |
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| Formato: | Artículo PeerReviewed |
| Lenguaje: | Español |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | http://pa.bibdigital.ucc.edu.ar/4959/1/A_Baena%20Cagnani.pdf |
| Aporte de: |
| Sumario: | Several deleterious effects have been described in asthma because of smoking: accelerated decline in lung function, more severe symptoms, impairment in quality of life and diminished therapeutic response to steroids. The harmful effect of tobacco smoking is not only on asthma but also on rhinitis playing a role in disease outcomes. Tobacco exposure can influence innate immunity diminishing innate production of antigenpresenting cells cytokines, as well as an impaired response to toll-like receptor ligands. Active smoking is associated with current symptoms of asthma and rhinitis and seems to be a risk factor for developing new asthma in patients with rhinitis. Tobacco smoking has been also found among the factors inducing nasal obstruction and decreased muco-ciliary clearance in nonallergic rhinitis. |
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