Cutaneous melanoma associated with previous nevus [Melanoma cutaneo asociado a nevo previo]

The malignant melanoma is a neoplasia originated from the melanocytes located in the skin and other locations. Even though there is not information regarding its incidence and prevalence in our country, its most important risk factors are known. The melanoma can originate de novo or from previous me...

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Autores principales: Gutierrez, María Paula, Barengo, Mónica, Mainardi, Claudio, Garay, Iliana, Kurpis, María, Ruiz Lascano, Alejandro
Formato: Artículo
Lenguaje:Español
Publicado: 2009
Materias:
R Medicina (General)
Acceso en línea:http://pa.bibdigital.ucc.edu.ar/4907/1/A_Gutierrez.pdf
Aporte de:
Producción Académica Universidad Católica de Córdoba (UCCor) de Universidad Católica de Córdoba
id I38-R144-4907
record_format dspace
spelling I38-R144-49072025-09-16T17:26:20Z http://pa.bibdigital.ucc.edu.ar/4907/ Cutaneous melanoma associated with previous nevus [Melanoma cutaneo asociado a nevo previo] Gutierrez, María Paula Barengo, Mónica Mainardi, Claudio Garay, Iliana Kurpis, María Ruiz Lascano, Alejandro R Medicina (General) The malignant melanoma is a neoplasia originated from the melanocytes located in the skin and other locations. Even though there is not information regarding its incidence and prevalence in our country, its most important risk factors are known. The melanoma can originate de novo or from previous melanocyte lesions. The concept that a melanocyte nevus can serve as a precursor lesion is supported by clinical and histological evidence. An observational, retrospective and analytical study was carried out in the Hospital Privado de Córdoba. The objective was to determine which is the frequency of association of malignant melanomas that develop on previous nevus. A total of 134 melanomas were analyzed. In 32 cases (24%), the melanomas were histologically associated with nevus, in individuals with Breslow's depth bigger than 1 mm the percentage of association was 16.3% while in those exhibiting Breslow smaller than 1 mm the percentage of association was 38.1%. Having evaluated the melanomas in relation to the Breslow and Clark classification, we observed that the nevus associated melanoma group showed less Breslow thickness and low Clark levels, which, by statistical analysis were shown to be significant predictors of the probabilty of finding this association (p < 0.027). This study demonstrates that the tumor thickness by itself is an independent predictive factor of the association melanoma-nevus. However, the rest of the variables studied did not throw significant results from the statistical point of view. In conclusion, patients must be educated for the control of new pigmented injuries as well as for the modification of preexisting nevi. 2009-12-31 info:eu-repo/semantics/article info:eu-repo/semantics/closedAccess application/pdf spa http://pa.bibdigital.ucc.edu.ar/4907/1/A_Gutierrez.pdf Gutierrez, María Paula, Barengo, Mónica, Mainardi, Claudio, Garay, Iliana, Kurpis, María and Ruiz Lascano, Alejandro (2009) Cutaneous melanoma associated with previous nevus [Melanoma cutaneo asociado a nevo previo]. Medicina, 69 (5). pp. 536-540. ISSN 16699106
institution Universidad Católica de Córdoba
institution_str I-38
repository_str R-144
collection Producción Académica Universidad Católica de Córdoba (UCCor)
language Español
orig_language_str_mv spa
topic R Medicina (General)
spellingShingle R Medicina (General)
Gutierrez, María Paula
Barengo, Mónica
Mainardi, Claudio
Garay, Iliana
Kurpis, María
Ruiz Lascano, Alejandro
Cutaneous melanoma associated with previous nevus [Melanoma cutaneo asociado a nevo previo]
topic_facet R Medicina (General)
description The malignant melanoma is a neoplasia originated from the melanocytes located in the skin and other locations. Even though there is not information regarding its incidence and prevalence in our country, its most important risk factors are known. The melanoma can originate de novo or from previous melanocyte lesions. The concept that a melanocyte nevus can serve as a precursor lesion is supported by clinical and histological evidence. An observational, retrospective and analytical study was carried out in the Hospital Privado de Córdoba. The objective was to determine which is the frequency of association of malignant melanomas that develop on previous nevus. A total of 134 melanomas were analyzed. In 32 cases (24%), the melanomas were histologically associated with nevus, in individuals with Breslow's depth bigger than 1 mm the percentage of association was 16.3% while in those exhibiting Breslow smaller than 1 mm the percentage of association was 38.1%. Having evaluated the melanomas in relation to the Breslow and Clark classification, we observed that the nevus associated melanoma group showed less Breslow thickness and low Clark levels, which, by statistical analysis were shown to be significant predictors of the probabilty of finding this association (p < 0.027). This study demonstrates that the tumor thickness by itself is an independent predictive factor of the association melanoma-nevus. However, the rest of the variables studied did not throw significant results from the statistical point of view. In conclusion, patients must be educated for the control of new pigmented injuries as well as for the modification of preexisting nevi.
format Artículo
author Gutierrez, María Paula
Barengo, Mónica
Mainardi, Claudio
Garay, Iliana
Kurpis, María
Ruiz Lascano, Alejandro
author_facet Gutierrez, María Paula
Barengo, Mónica
Mainardi, Claudio
Garay, Iliana
Kurpis, María
Ruiz Lascano, Alejandro
author_sort Gutierrez, María Paula
title Cutaneous melanoma associated with previous nevus [Melanoma cutaneo asociado a nevo previo]
title_short Cutaneous melanoma associated with previous nevus [Melanoma cutaneo asociado a nevo previo]
title_full Cutaneous melanoma associated with previous nevus [Melanoma cutaneo asociado a nevo previo]
title_fullStr Cutaneous melanoma associated with previous nevus [Melanoma cutaneo asociado a nevo previo]
title_full_unstemmed Cutaneous melanoma associated with previous nevus [Melanoma cutaneo asociado a nevo previo]
title_sort cutaneous melanoma associated with previous nevus [melanoma cutaneo asociado a nevo previo]
publishDate 2009
url http://pa.bibdigital.ucc.edu.ar/4907/1/A_Gutierrez.pdf
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