Genotoxicity tests on the compounds of polyethylene glycol terephthalate (PET): Dimethylterephthalate (DMT) and terephtalic acid (TPA)

Dimethylterephthalate (DMT) and terephtalic acid (TPA), the main compounds of polyethylene glycol terephthalate (PET) were evaluated for genotoxicity and mutagenicity in the Ames test, UDS by liquid scintillation counting, and micronuclei induced in binucleate human lymphocytes. Data failed to show...

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Detalles Bibliográficos
Autor principal: Lerda, Daniel Enrique
Formato: Artículo
Lenguaje:Español
Publicado: 1996
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Acceso en línea:http://pa.bibdigital.ucc.edu.ar/3720/1/A_Lerda.pdf
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Sumario:Dimethylterephthalate (DMT) and terephtalic acid (TPA), the main compounds of polyethylene glycol terephthalate (PET) were evaluated for genotoxicity and mutagenicity in the Ames test, UDS by liquid scintillation counting, and micronuclei induced in binucleate human lymphocytes. Data failed to show that DMT and TPA at different concentrations (0.5, 5, 50 and 500 μg ml-1) had any genotoxic and or mutagenic effects. Further research should be carried on so that in vivo genotoxic properties of the PET precursors can be determined.