Bilateral occipital calcification, epilepsy and coeliac disease: clinical and neuroimaging features of a new syndrome
Twenty patients affected by bilateral occipital cortical-subcortical calcification (BOC) are described, 19 (95%) had epilepsy. In 8 of 16 cases studied, intestinal biopsy revealed coeliac disease. Fourteen patients had occipital partial epilepsy with a relatively benign outcome, while 4 patients w...
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| Autores principales: | , , , , , , , , , , |
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| Formato: | Artículo acceptedVersion |
| Lenguaje: | Español |
| Publicado: |
1993
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| Materias: | |
| Acceso en línea: | http://pa.bibdigital.ucc.edu.ar/3711/1/A_Magaudda_DallaBernardina_DeMarco_Sfaello_Longo_Colamaria_Daniele_Tortorella_Tata_Pierri_Meduri.pdf |
| Aporte de: |
| Sumario: | Twenty patients affected by bilateral occipital cortical-subcortical calcification (BOC) are described, 19 (95%) had
epilepsy. In 8 of 16 cases studied, intestinal biopsy revealed coeliac disease.
Fourteen patients had occipital partial epilepsy with a relatively benign outcome, while 4 patients were affected by a severe form of epilepsy, with very frequent, drug-resistant, generalised and partial seizures with mental deterioration. One patient had a single episode of
convulsive status epilepticus at four months of age. The neurological examination was normal in all patients. CT
showed flocculo-nodular, cortico-subcortical BOC, without enhancement and without lobar or hemispheric atrophy.
MRI was normal. The clinical and neuroimaging features of these patients are different therefore from those with the
Sturge-Weber Syndrome. The study confirms a high prevalence of coliac disease in patients with BOC, but the relationship between these two pathologies still needs to be clarified. |
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