Structural elements in the Gag polyprotein of feline immunodeficiency virus involved in Gag self-association and assembly

The Gag polyprotein of feline immunodeficiency virus (FIV) assembles at the plasma membrane of the infected cells. Since the FIV Gag domains whose interaction promotes Gag multimerization have not been identified, we generated a series of Gag subdomains which were tested for their ability to associa...

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Detalles Bibliográficos
Autores principales: Abdusetir Cerfoglio, Juan C., González, Silvia A., Affranchino, José L.
Formato: Artículo
Lenguaje:Inglés
Publicado: Universidad de Belgrano - Facultad de Ciencias Exactas y Naturales - Proyectos de Investigación 2014
Materias:
Gag polyprotein
Feline immunodeficiency virus
Lentivirus assembly
Montaje Lentivirus
poliproteína Gag
virus de la inmunodeficiencia felina
Acceso en línea:http://repositorio.ub.edu.ar/handle/123456789/2911
Aporte de:
Repositorio Institucional - Universidad de Belgrano (UB) de Universidad de Belgrano
Descripción
Sumario:The Gag polyprotein of feline immunodeficiency virus (FIV) assembles at the plasma membrane of the infected cells. Since the FIV Gag domains whose interaction promotes Gag multimerization have not been identified, we generated a series of Gag subdomains which were tested for their ability to associate with full-length Gag and be recruited into extracellular virus-like particles (VLPs).

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