A pilot cross-sectional study to investigate the biomarker potential of phosphorylated neurofilament-H and immune mediators of disability in patients with 5 year relapsing-remitting multiple sclerosis

Introduction: Multiple sclerosis is the most prevalent chronic autoimmune disease of the central nervous system with the first clinical symptoms typically appearing in early adulthood, and affecting over 2 million people worldwide (1). Relapsing-remitting multiple sclerosis (RRMS) is the current...

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Detalles Bibliográficos
Autores principales: Herrera, María Inés, Kölliker Frers, Rodolfo, Otero Losada, Matilde, Pérez Lloret, Santiago, Filippo, Macarena, Tau, Julia, Capani, Francisco, Villa, Andrés M.
Formato: Artículo
Lenguaje:Inglés
Publicado: Frontiers In 2019
Materias:
ESCLEROSIS MULTIPLE
DISCAPACIDAD
CITOQUINAS
ENFERMOS
ENFERMEDADES AUTOINMUNES
Acceso en línea:https://repositorio.uca.edu.ar/handle/123456789/9158
Aporte de:
Repositorio Institucional de la Universidad Católica Argentina (UCA) de Universidad Católica Argentina
Descripción
Sumario:Introduction: Multiple sclerosis is the most prevalent chronic autoimmune disease of the central nervous system with the first clinical symptoms typically appearing in early adulthood, and affecting over 2 million people worldwide (1). Relapsing-remitting multiple sclerosis (RRMS) is the current criteria-based most prevalent form of the three clinical presentations of multiple sclerosis (MS), relapsing-remitting, converted to secondary progressive, and primary progressive. It is characterized by neurologic worsening attacks or relapses followed by apparent recovery periods of masked progression of the disease...

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