Inhibition of TRPC6 channels ameliorates renal fibrosis and contributes to renal protection by soluble klotho

Abstract: Fibrosis is an exaggerated form of tissue repair that occurs with serious damage or repetitive injury and ultimately leads to organ failure due to the excessive scarring. Increased calcium ion entry through the TRPC6 channel has been associated with the pathogenesis of heart and glomerular...

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Autores principales: Wu, Yueh-Lin, Xie, Jian, An, Sung-Wan, Oliver, Noelynn, Barrezueta, Nestor X., Lin, Mei-Hsiang, Birnbaumer, Lutz, Huang, Chou-Long
Formato: Artículo
Publicado: Elsevier 2019
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