Antidepression action of BDNF requires and is mimicked by Gαi1/3 expression in the hippocampus

Abstract: Stress-related alterations in brain-derived neurotrophic factor (BDNF) expression, a neurotrophin that plays a key role in synaptic plasticity, are believed to contribute to the pathophysiology of depression. Here, we show that in a chronic mild stress (CMS) model of depression the Gαi1 an...

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Detalles Bibliográficos
Autores principales: Marshall, John, Zhou, Xiao-Zhong, Chen, Gang, Yang, Su-Qing, Li, Ya, Wang, Yin, Zhang, Zhi-Qing, Jiang, Qin, Birnbaumer, Lutz, Cao, Cong
Formato: Artículo
Lenguaje:Español
Publicado: National Academy of Sciences 2019
Materias:
DEPRESION
HIPOCAMPO
PROTEINAS
NEURONAS
Acceso en línea:https://repositorio.uca.edu.ar/handle/123456789/8699
Aporte de:
Repositorio Institucional de la Universidad Católica Argentina (UCA) de Universidad Católica Argentina

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