Balance of Go1α and Go2α expression regulates motor function via the striatal dopaminergic system

Abstract: The heterotrimeric G-protein Go with its splice variants, Go1α and Go2α, seems to be involved in the regulation of motor function but isoform-specific effects are still unclear. We found that Go1α-/- knockouts performed worse on the rota-rod than Go2α-/- and wild-type (WT) mice. In Go1+2α-...

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Autores principales: Baron, Jens, Bilbao, Ainhoa, Hörtnagl, Heide, Birnbaumer, Lutz, Leixner, Sarah, Spanagel, Rainer, Ahnert-Hilger, Gudrun, Brunk, Irene
Otros Autores: 0000-0002-3301-2628
Formato: Artículo
Lenguaje:Inglés
Publicado: Wiley 2019
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Acceso en línea:https://repositorio.uca.edu.ar/handle/123456789/8694
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