M1 macrophage polarization is dependent on TRPC1-mediated calcium entry
Abstract: Macrophage plasticity is essential for innate immunity, but in-depth signaling mechanism(s) regulating their functional phenotypes are ill-defined. Here we report that interferon (IFN) γ priming of naive macrophages induces store-mediated Ca2+ entry and inhibition of Ca2+ entry impairs pol...
Guardado en:
| Autores principales: | Chauhan, Arun, Sun, Yuyang, Sukumaran, Pramod, Quenum Zangbede, Fredice O., Jondle, Christopher N., Sharma, Atul, Evans, Dustin L., Chauhan, Pooja, Szlabick, Randolph E., Aaland, Mary O., Birnbaumer, Lutz, Sharma, Jyotika, Singh, Brij B., Mishra, Bibhuti B. |
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| Formato: | Artículo |
| Lenguaje: | Inglés |
| Publicado: |
Elsevier (Cell Press)
2019
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| Materias: | |
| Acceso en línea: | https://repositorio.uca.edu.ar/handle/123456789/8685 |
| Aporte de: |
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