Gao is a major determinant of cAMP signaling in the pathophysiology of movement disorders

Abstract: The G protein alpha subunit o (Gao) is one of the most abundant proteins in the nervous system, and pathogenic mutations in its gene (GNAO1) cause movement disorder. However, the function of Gao is ill defined mechanistically. Here, we show that Gao dictates neuromodulatory responsivenes...

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Autores principales: Muntean, Brian S., Masuho, Ikuo, Dao, Maria, Blakely, Randy D., Grill, Brock, Martemyanov, Kirill A., Sutton, Laurie, Zucca, Stefano, Iwamoto, Hideki, Patil, Dipak N., Wang, Dandan, Birnbaumer, Lutz
Formato: Artículo
Lenguaje:Inglés
Publicado: Elsevier 2021
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Acceso en línea:https://repositorio.uca.edu.ar/handle/123456789/11617
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