THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors
Abstract: Peripheral T-cell lymphomas (PTCL) are aggressive diseases with poor response to chemotherapy and dismal survival. Identification of effective strategies to target PTCL biology represents an urgent need. Here we report that PTCL are sensitive to transcription-targeting drugs, and, in parti...
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| Autores principales: | Cayrol, María Florencia, Praditsuktavorn, Pannee, Fernando, Tharu M., Kwiatkowski, Nicholas, Marullo, Rosella, Calvo Vidal, M. Nieves, Phillip, Jude, Pera, Benet, Yang, Shao Ning, Takpradit, Kaipol, Roman, Lidia, Gaudiano, Marcello, Crescenzo, Ramona, Ruan, Jia, Inghirami, Giorgio, Zhang, Tinghu, Cremaschi, Graciela A., Gray, Nathanael S., Cerchietti, Leandro |
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| Formato: | Artículo |
| Lenguaje: | Inglés |
| Publicado: |
Springer Nature
2019
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| Materias: | |
| Acceso en línea: | https://repositorio.uca.edu.ar/handle/123456789/8653 |
| Aporte de: |
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