Response to Letter to the Editor “On the targets of fluoxetine”
We read the Letter to the Editor entitled “On the targets of Flu-oxetine” by James M. Brimson and Stephen T. Safrany referred to our review entitled “Immunomodulatory effects of fluoxetine: Anew potential pharmacological action for a classic antidepressantdrug?”.The authors consider that many of the...
Guardado en:
| Autores principales: | , , |
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| Formato: | Artículo |
| Lenguaje: | Inglés |
| Publicado: |
Elsevier
2025
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| Acceso en línea: | https://repositorio.uca.edu.ar/handle/123456789/19332 |
| Aporte de: |
| Sumario: | We read the Letter to the Editor entitled “On the targets of Flu-oxetine” by James M. Brimson and Stephen T. Safrany referred to our review entitled “Immunomodulatory effects of fluoxetine: Anew potential pharmacological action for a classic antidepressantdrug?”.The authors consider that many of the effects described forfluoxetine could be due to the activation of sigma-1 receptorsuggesting that this receptor could be the “Novel receptor” on lym-phocytes proposed in our review. While sigma receptors activationis mainly known for their effect on the nervous system, the presence of this receptor on non-neuronal tissues, including immunesystem has been described. |
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