Functional compensation of P/Q by N-type channels blocks short-term plasticity at the calyx of Held presynaptic terminal

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Calcium channels of the P/Q subtype mediate transmitter release at the neuromuscular junction and at many central synapses, such as the calyx of Held. Transgenic mice in which α1A channels are ablated provide a powerful tool with which to test compensatory mechanisms at the synapse and to explore me...

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Detalles Bibliográficos
Autores principales: González Inchauspe, C., Martini, F.J., Forsythe, I.D., Uchitel, O.D.
Formato: Artículo publishedVersion
Publicado: 2004
Materias:
Calcium currents
Calyx of Held
Facilitation
Knock-out mice
P/Q channels
Synaptic transmission
calcium channel N type
calcium channel P type
calcium channel Q type
calcium ion
animal tissue
article
calcium current
channel gating
facilitation
knockout mouse
mouse
nerve cell plasticity
nonhuman
presynaptic membrane
priority journal
synaptosome
transgenic mouse
Animals
Brain Stem
Calcium
Calcium Channels, N-Type
Calcium Channels, P-Type
Calcium Channels, Q-Type
Evoked Potentials
Mice
Mice, Knockout
Neuronal Plasticity
Presynaptic Terminals
Protein Subunits
Synapses
Synaptic Transmission
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_02706474_v24_n46_p10379_GonzalezInchauspe
https://repositoriouba.sisbi.uba.ar/gsdl/cgi-bin/library.cgi?a=d&c=artiaex&d=paper_02706474_v24_n46_p10379_GonzalezInchauspe_oai
Aporte de:
Repositorio Digital de la Universidad de Buenos Aires (UBA) de Universidad de Buenos Aires

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