Molecular and functional evidence for in vitro cytokine enhancement of human and murine target cell sensitivity to glucocorticoids: TNF-α priming increases glucocorticoid inhibition of TNF-α-induced cytotoxicity/apoptosis

Mostrar todas las versiones(3)

Cytokine-induced glucocorticoid secretion and glucocorticoid inhibition of cytokine synthesis and pleiotropic actions act as important safeguards in preventing cytokine overreaction. We found that TNF-α increased glucocorticoid-induced transcriptional activity of the glucocorticoid receptor (GR) via...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Costas, M., Trapp, T., Pereda, M.P., Sauer, J., Rupprecht, R., Nahmod, V.E., Reul, J.M.H.M., Holsboer, F., Arzt, E.
Formato: Artículo publishedVersion
Publicado: 1996
Materias:
apoptosis
cytokines
glucocorticoid receptor
glucocorticoid response element
TNF-α
glucocorticoid
tumor necrosis factor alpha
animal cell
article
cytotoxicity
human
human cell
immune response
immunoregulation
mouse
nonhuman
priority journal
target cell
transcription regulation
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00219738_v98_n6_p1409_Costas
https://repositoriouba.sisbi.uba.ar/gsdl/cgi-bin/library.cgi?a=d&c=artiaex&d=paper_00219738_v98_n6_p1409_Costas_oai
Aporte de:
Repositorio Digital de la Universidad de Buenos Aires (UBA) de Universidad de Buenos Aires

Ejemplares similares

Ejemplares similares