InVet. 2014, 16 (2): 63-68 INTERFERENCIAS ISSN 1514-6634 (impreso) ...

The fructosamine serum concentration reflects the degree of glycemic control obtained during a\npreceding period. Usually, the presence of hemoglobin or bilirrubin in blood samples, could cause\ninterferences in the laboratory analytical assays.Thus, we investigated the possible interferences\non fr...

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Autores principales: Colla, C., Rodriguez, J., Rabe, G., Patalano, C., Perassi, M., Bordone, F., Cerrutti, J.
Formato: Artículo publishedVersion
Lenguaje:Español
Publicado: Universidad de Buenos Aires. Facultad de Ciencias Veterinarias 2014
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Acceso en línea:http://repositoriouba.sisbi.uba.ar/gsdl/cgi-bin/library.cgi?a=d&c=pveterinaria/invet&cl=CL1&d=HWA_1275
https://repositoriouba.sisbi.uba.ar/gsdl/collect/pveterinaria/invet/index/assoc/HWA_1275.dir/1275.PDF
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Sumario:The fructosamine serum concentration reflects the degree of glycemic control obtained during a\npreceding period. Usually, the presence of hemoglobin or bilirrubin in blood samples, could cause\ninterferences in the laboratory analytical assays.Thus, we investigated the possible interferences\non fructosamine determinations in serum from healthy cats and dogs. To testing and quantify the interference, we construct interferograms adding increased concentrations of hemoglobin or bilirrubin to serum pools of cats or dogs. We tested serum hemoglobin concentrations from 0.19 to 7.5 g/l in feline sera and 0.16 to 6.10 g/l in canine sera. The bilirrubin testing was done from 6 to 600 mg/l in both species sera. The results had shown a hemoglobin positive and additive interference in feline sera (?1.60 g/l) and a negative interference in canine sera (?1.20 g/l). In addition both species had shown positive and additive bilirrubin interferences (?30 mg/l for feline sera and ?150 mg/l for canine sera).