Recubrimientos antimicrobianos vía sol-gel: su aplicación en el control de formación de biofilms
Hybrid organic-inorganic materials development is nowadays a widely studied subject. The\ninvestigation and application of these materials include different areas such as biotechnology,\npharmacy and medicine. The proposed hypothesis in this thesis was: the modification of surfaces\nand materials us...
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| Formato: | Tesis doctoral acceptedVersion |
| Lenguaje: | Español |
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Facultad de Farmacia y Bioquímica
2015
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| Acceso en línea: | http://repositoriouba.sisbi.uba.ar/gsdl/cgi-bin/library.cgi?a=d&c=posgraafa&cl=CL1&d=HWA_1159 http://repositoriouba.sisbi.uba.ar/gsdl/collect/posgraafa/index/assoc/HWA_1159.dir/1159.PDF |
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| Sumario: | Hybrid organic-inorganic materials development is nowadays a widely studied subject. The\ninvestigation and application of these materials include different areas such as biotechnology,\npharmacy and medicine. The proposed hypothesis in this thesis was: the modification of surfaces\nand materials using different silicon oxide precursors and organic or inorganic counterparts as well\nas antimicrobial agents, can control bacterial colonization in those modified surfaces and materials\nand in the surrounding media, in order to apply them in the sanitary and household environment.\nIn order to satisfy these objectives, two point of view have been taken into account. Talking\nabout modified superficial physicochemical properties, point of zero charge of different modified\nsurfaces and bacterial membranes have been analyzed and compared. Talking about antimicrobial\nagents incorporation, these agents where immobilized in the surface to get an antimicrobial effect\nby direct contact or they were released to the surface in a controlled way. To achieve this last goal,\nthe antimicrobial agents were adsorbed in nanostructures such as chitin nanowhiskers or\nantimicrobial metallic nanoparticles (Copper nanoparticles) were included in the modified matrix |
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