Osteocyte alterations induce osteoclastogenesis in an in vitro model of gaucher disease
Gaucher disease (GD) is caused by mutations in the glucosylceramidase β (GBA 1) gene that confer a deficient level of activity of glucocerebrosidase (GCase). This deficiency leads to the accumulation of the glycolipid glucocerebroside in the lysosomes of cells, mainly in the monocyte/macrophage line...
Guardado en:
| Autores principales: | Bondar, Constanza María, Ormazabal, Maximiliano, Crivaro, Andrea Natalia, Ferreyra Compagnucci, Malena, Delpino, María Victoria, Rozenfeld, Paula Adriana, Mucci, Juan Marcos |
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| Formato: | Articulo |
| Lenguaje: | Inglés |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/87705 |
| Aporte de: |
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