BDA-410 Treatment Reduces Body Weight and Fat Content by Enhancing Lipolysis in Sedentary Senescent Mice

Loss of muscle mass and force with age leads to fall risk, mobility impairment, and reduced quality of life. This article shows that BDA-410, a calpain inhibitor, induced loss of body weight and fat but not lean mass or skeletal muscle proteins in a cohort of sedentary 23-month-old mice. Food and wa...

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Detalles Bibliográficos
Autores principales: Pereyra, Andrea Soledad, Wang, Zhong Min, Messi, María Laura, Zhang, Tan, Wu, Hanzhi, Register, Thomas C., Forbes, Elizabeth, Devarie Baez, Nelmi O., Files, Daniel Clark, Abba, Martín Carlos, Furdui, Cristina, Delbono, Osvaldo
Formato: Articulo
Lenguaje:Inglés
Publicado: 2017
Materias:
Ciencias Médicas
Aging
Body fat
Calpain
Sarcopenia
Skeletal muscle
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/87609
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

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