Progesterone receptor isoform ratio: a breast cancer prognostic and predictive factor for antiprogestin responsiveness

<b>Background:</b> Compelling evidence shows that progestins regulate breast cancer growth. Using preclinical models, we demonstrated that antiprogestins are inhibitory when the level of progesterone receptor isoform A (PR-A) is higher than that of isoform B (PR-B) and that they might st...

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Detalles Bibliográficos
Autores principales: Rojas, Paola A., May, María, Sequeira, Gonzalo R., Elia, Andrés, Alvarez, Michelle, Martínez, Paula, González, Pedro Horacio, Hewitt, Stephen, He, Xiaping, Perou, Charles M., Molinolo, Alfredo, Gibbons, Luz, Abba, Martín Carlos, Gass, Hugo, Lanari, Claudia
Formato: Articulo
Lenguaje:Inglés
Publicado: 2017
Materias:
Ciencias Médicas
breast cancer
progesterone receptor isoform
molecular characteristics
clinical characteristics
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/87477
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

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