Shedding light on venoarterial PCO<sub>2</sub> gradient

As an expression on Fick’s principle, the reduction in cardiac output is associated with a parallel increase in both mixed venoarterial CO<sub>2</sub> content diference (C<sub>mv-a</sub>CO<sub>2</sub>) and arterial-mixed venous oxygen content diference (C<sub&g...

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Detalles Bibliográficos
Autores principales: Dubin, Arnaldo, Pozo, Mario Omar
Formato: Articulo
Lenguaje:Inglés
Publicado: 2017
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Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/87306
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Sumario:As an expression on Fick’s principle, the reduction in cardiac output is associated with a parallel increase in both mixed venoarterial CO<sub>2</sub> content diference (C<sub>mv-a</sub>CO<sub>2</sub>) and arterial-mixed venous oxygen content diference (C<sub>a-mv</sub>O<sub>2</sub>). Nevertheless, disproportioned elevations in C<sub>mv-a</sub>CO<sub>2</sub> compared to those of C<sub>a-mv</sub>O<sub>2</sub> ensue when the anaerobic threshold is reached. Tis results from anaerobic CO<sub>2</sub> production, secondary to the bufering of anaerobically generated protons by bicarbonate.